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Saracatinib 
N-​(5-​chloro-​1,​3-​benzodioxol-​4-​yl)-​7-​[2-​(4-​methyl-​1-​piperazinyl)ethoxy]-​5-​[(tetrahydro-​2H-​pyran-​4-​yl)oxy]-​4-​quinazolinamine
(CAS 379231-04-6)
Description:

Saracatinib is a dual inhibitor of the tyrosine kinases c-Src and Abl (IC50 = 2.7 and 30 nM, respectively). It less effectively inhibits other receptor and non-receptor tyrosine kinases as well as assorted serine/threonine kinases. Saracatinib is orally available and blocks cell motility, migration, adhesion, invasion, proliferation, differentiation, and survival. Through its effects on c-Src, it reduces osteoclast bone resorption. Saracatinib also blocks denque virus RNA replication through its effect on Fyn kinase.

 

Product No. KT20010 
Product Name Saracatinib 
Synonyms AZD 0530
Formal Name N-​(5-​chloro-​1,​3-​benzodioxol-​4-​yl)-​7-​[2-​(4-​methyl-​1-​piperazinyl)ethoxy]-​5-​[(tetrahydro-​2H-​pyran-​4-​yl)oxy]-​4-​quinazolinamine
CAS Number 379231-04-6
Molecular Formula C27H32ClN5O5
Formula Weight 542.0
Formulation A crystalline solid
Purity 98%min
Stability 1 year
Storage -20°C
Shipping USD45 for Europe and USA. No shipping charge once amount reach USD500.
Quality Control HNMR,CNMR,LCMS,HPLC,IR,etc.
Price & Availability In Stock. Price Negotiated.
 
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