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Erlotinib 
N-​(3-​ethylnylphenyl)-​6,​7-​bis(2-​methoxyethoxy)-​4-​quinazolinamine
(CAS 183321-74-6)
Description:

Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 µM). This inhibits tumor growth in human head and neck carcinoma (HN5) tumor xenografts in mice with an ED50 value of 9 mg/kg. Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 µM) and JAK2 mutant JAK2V617F (IC50 = 5 µM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia. The drug form of Erlotinib, Tarceva™, is used to treat certain forms of cancer, including non-small cell lung cancer.

 

Product No. KT20004 
Product Name Erlotinib 
Synonyms NSC 718781; OSI-744; R-1415; OSI744; OSI 744; R1415; R 1415
Formal Name N-​(3-​ethylnylphenyl)-​6,​7-​bis(2-​methoxyethoxy)-​4-​quinazolinamine
CAS Number 183321-74-6
Molecular Formula C22H23N3O4
Formula Weight 393.4
Formulation A crystalline solid
Purity 98%min
Stability 1 year
Storage -20°C
Shipping USD45 for Europe and USA. No shipping charge once amount reach USD500.
Quality Control HNMR,CNMR,LCMS,HPLC,IR,etc.
Price & Availability In Stock. Price Negotiated.
 
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