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Flutamide 
2-Methyl-N-(4-nitro-3-[trifluoromethyl]phenyl)propanamide
(CAS 13311-84-7)
Description:

Flutamide is an antiandrogen drug, with its active metablolite binding at androgen receptor with Ki values of 55 nM, and primarily used to treat prostate cancer.
Target: androgen receptor
in vitro: Flutamide (Eulexin) is an antiandrogen drug. Flutamide-OH, the active metabolite of flutamide, directly binds at rat anterior pituitary androgen receptor with Ki values of 55 nM. lutamide does not affect the proliferation of an androgen-sensitive clone of the mouse mammary carcinoma Shionogi SC-l 15 cells in culture, shows only antiandrogenic effect, but not androgenic effect. Flutamide provides treatment for prostate cancer when used along with leuprolide.
in vivo: Flutamide causes a markedly reduction in rat ventral prostate weight from 319 mg to 245 mg. A combination of flutamide and LHRH agonist induces an additive effect with a decrease in prostate weight to 101 mg, and an marked drop in prostatic ODC activity.

 

Product No. KT20509 
Product Name Flutamide 
Synonyms SCH 13521; Eulexin; Flutamin; Drogenil
Formal Name 2-Methyl-N-(4-nitro-3-[trifluoromethyl]phenyl)propanamide
CAS Number 13311-84-7
Molecular Formula C11H11F3N2O3
Formula Weight 276.21
Formulation A crystalline solid
Purity 98%min
Stability 2 years
Storage -20°C
Shipping USD45 for Europe and USA. No shipping charge once amount reach USD500
Quality Control HNMR,CNMR,LCMS,HPLC,IR,etc.
Price & Availability In Stock. $100/25g
 
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